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Calibration of Spectral Imaging Devices With Oxygenation-Controlled Phantoms: Introducing a Simple Gel-Based Hemoglobin Model
2019
Frontiers in Physics
An optical phantom model with stable oxygen saturation (StO2) and optical properties (OPs) is the key for quick and accurate calibration of spectral imaging devices. Toward this goal, we have developed gel-based phantoms using Agarose, polystyrene microsphere, purified hemoglobin, and yeast. Theoretical values of OPs were calculated by applying Beer Lambert law and Mie theory whereas a robust fitting algorithm was used to extract StO2. Stability of OPs and StO2 in the phantoms was validated
doi:10.3389/fphy.2019.00192
fatcat:l5ln53uz3revrnk7dbeahsnie4