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The Journal of Bone and Joint Surgery
D amage to articular cartilage is a common injury, for which there is no effective treatment. Our aims were to investigate the temporal sequence of the repair of articular cartilage and to define a critical-size defect. Full-thickness defects were made in adult male New Zealand white rabbits. The diameter (1 to 4 mm) of the defects was varied in order to determine the effect that the size and depth of the defect had on its healing. The defects were made in the femoral groove of the knee withdoi:10.1302/0301-620x.84b4.11631 pmid:12043787 fatcat:f2n5uoizqreg7czxf2jxpjd3hi