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Toxic epidermal necrolysis is a cutaneous drug reaction which is a severe adverse effect that predominantly involves the skin and mucous membrane. Phenytoin is an anti-epileptic medication that belongs to the hydantoin class. Here we are going to present a case of 50-year-old male patient with phenytoin induced toxic epidermal necrolysis. The outcome of this study was to determine the severity of the adverse reaction and its management to improve the patient condition. Keywords: Toxic epidermaldoi:10.22270/jddt.v12i4-s.5595 fatcat:epjy2jiccjardjcpipg2k6vuqu