Elevated Cell Wall Serine in Pleiotropic Staphylococcal Mutants

Ruth Z. Korman
1966 Journal of Bacteriology  
KoRMAN, RuTH Z. (Cornell University, Ithaca, N.Y.). Elevated cell wall serine in pleiotropic staphylococcal mutants. J. Bacteriol. 92:762-768. 1966.-Physically purified cell walls were prepared from two staphylococcal strains and from pleiotropic variants derived from them. The quantitative amino acid and amino sugar content of these walls is reported. The pleiotypes, which are identified culturally by their failure to elaborate coagulase, their resistance to bacteriophage, and their
more » ... nd their sensitivity to mannitol, have altered molar ratios of amino acids and amino sugars in their cell walls. In comparison with lysine content, the serine content of the mutant wall is elevated and the glycine content is reduced. The glucosamine content is reduced also. It is postulated that the pleiotropic mutants possess an altered cell wall biosynthetic pathway. Acad. Sci. U.S. 53:207-214. 768 KORMAN on May 9, 2020 by guest
doi:10.1128/jb.92.3.762-768.1966 fatcat:mzmwqesxajfehlpontrvvq5vru