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Prevention of Methylprednisolone Acetate-Induced Osteoporosis with Calcium Administration in Rat Model
Acta Medica Iranica
Glucocorticoid steroids are widely used as anti-inflammatory and immunosuppressive medications and are well known to induce osteoporosis. In Present study 24 rats were randomly divided into four groups (n=6): Group A (control), Group B (sham)that was treated only by normal saline for 1 month.Group C that was treated by methylprednisolone acetate alone (0.2 mg/kg) for 1 month. Group D that was treated by methylprednisolone acetate (0.2 mg/kg) and oral calcium supplementation (15 mg/kg) for 1doaj:b61482a297854d42b158521bf45e9870 fatcat:vcwoxj3jzzdvldxy2mttybdtvu