Please cite this article as: Butorina, A., Prokofyev, A., Nazarova, M., Litvak, V., Stroganova, T., The mirror illusion induces high gamma oscillations in the absence of movement, NeuroImage (2014), Sretenka 29, Moscow, Russian Federation, 107045, Phone/fax number: +74956329866 Running title: Mirror illusion and high gamma oscillations Highlights:  We examined movement-related high gamma oscillations (HGO) in healthy humans with MEG  Real hand movements produced sensorimotor HGO in the

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... ateral hemisphere  Similar HGO response was triggered by mirror visual feedback from a moving hand  HGO in sensorimotor cortex may reflect the neural mechanism of mirror-hand illusion Abstract We tested whether mirror visual feedback (MVF) from a moving hand induced high gamma oscillations (HGO) response in the hemisphere contralateral to the mirror and ipsilateral to the selfpaced movement. MEG was recorded in 14 subjects under three conditions: bilateral synchronous movements of both index fingers (BILATERAL), movements of the right hand index finger while observing the immobile left index finger (NOMIRROR), and movements of the right hand index finger while observing its mirror reflection (MIRROR). The right hemispheric spatiospectral regions of interests (ROI) in the sensor space, sensitive to bilateral movements, were found by statistical comparison of the BILATERAL spectral responses to baseline. For these ROIs, the post-movement HGO responses were compared between the MIRROR and NOMIRROR conditions. We found that MVF from the moving hand, similarly to the real movements of the opposite hand, induced HGO (55-85Hz) in the sensorimotor cortex. This MVF effect was frequency-specific and did not spread to oscillations in other frequency bands. This is the first study demonstrating movement-related HGO induced by MVF from the moving hand in absence of proprioceptive feedback signaling. Our findings support the hypothesis that MVF can trigger the feedback-based control processes specifically associated with perception of one's own movements.