A portable system has been developed for the control and the readout of a 64 64 pixel silicon hybrid detector (1.1 1.1 cm 2 active area), bump-bonded to the Medipix1 readout chip. This system, originally designed for biomedical imaging applications, is based on a standard commercial digital I/O board and a compact dedicated interface ( -MUROS), connected to a portable (or desktop) PC. The Medipix1 chip is hosted in a removable chip carrier directly placed on the -MUROS board. This board is a

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... plified version of the MUROS1 readout board already developed in the framework of the Medipix collaboration. A user-friendly software system (Medisoft 3.3) has been written to provide control of the system and image acquisition, display, and processing. This complete hardware/software imaging system has been used with or without high-resolution collimators, with laboratory and sources for test purposes, and represents the portable version of the desktop imaging system developed for -autoradiography. The system description and complete imaging tests are presented.