Estudo comparativo entre as metodologias preconizadas pelo CLSI e pelo EUCAST para avaliação da atividade antifúngica

Marcos Aurélio Stoppa, Luciana Assirati Casemiro, Adriana Helena Chicharo Vinholis, Wilson Roberto Cunha, Márcio Luis Andrade e Silva, Carlos Henrique Gomes Martins, Niege Araçari Jacometti Cardoso Furtado
2009 Química Nova  
Estudo comparativo EntrE as mEtodologias prEconizadas pElo clsi E pElo Eucast para avaliação da atividadE antifúngica marcos aurélio stoppa, luciana assirati casemiro, adriana Helena chicharo vinholis, Wilson roberto cunha, márcio luis andrade e silva e carlos Henrique gomes martins * Universidade de Franca, 14404-600 Franca -SP, Brasil niege araçari Jacometti cardoso furtado Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, 14040-903 Ribeirão Preto -SP, Brasil.
more » ... Preto -SP, Brasil. Recebido em 2/4/08; aceito em 8/8/08; publicado na web em 5/2/09 COMPARATIVE STUDY OF THE RECOMMENDED METHODOLOGIES BY CLSI AND EUCAST FOR ACTIVITY EVALUATION ANTIFUNGAL. The international organizations CLSI and EUCAST developed reference methodologies for activity evaluation antifungal. The aim of this work was to compare the recommended methodologies by the CLSI and EUCAST in the antifungal activity evaluation of crude extracts of Azadirachta indica and green propolis. The results showed that the MIC values determined by the EUCAST methodology were smaller than that determined by the CLSI. Nevertheless, both methodologies were satisfactory to detect and evaluate antifungal activity of the crude extracts and isolated compounds. The EUCAST methodology showed advantage by making possible to obtain results in less time.
doi:10.1590/s0100-40422009000200038 fatcat:neamtyld5zc37axepk3y52axim