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Lack of tailless leads to an increase in expression variability in Drosophila embryos
2013
Developmental Biology
Developmental processes are robust, or canalised: dynamic patterns of gene expression across space and time are regulated reliably and precisely in the presence of genetic and environmental perturbations. It remains unclear whether canalisation relies on specific regulatory factors (such as heat-shock proteins), or whether it is based on more general redundancy and distributed robustness at the network level. The latter explanation implies that mutations in many regulatory factors should
doi:10.1016/j.ydbio.2013.01.010
pmid:23333944
pmcid:PMC3635121
fatcat:ypbeqzxehbeyzbeaqno45v6day