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SWITCHES: Searchable Web Interface for Topologies of CHEmical Switches
[article]
2020
bioRxiv
pre-print
Bistable biochemical switches are key motifs in cellular state decisions and long-term storage of cellular 'memory'. There are a few known biological switches that have been well characterized, however these examples are insufficient for systematic surveys of properties of these important systems. Here we present a resource of all possible bistable biochemical reaction networks with up to 6 reactions between 3 molecules, and 3 reactions between 4 molecules. Over 35,000 reaction topologies were
doi:10.1101/2020.08.04.232371
fatcat:75o4nvlwzjd25a43ewzbzlofiu