The morphological manifestations of neuroplastic variability of projection neurons were studied under conditions of experimental destruction of various structures of the central nervous system in animals. Various forms of pathological manifestations of neuroplastic variability of "survivors" (after exposure to a damaging factor) marked through the axonal transport system of neurons are shown. Marked nerve cells of an unusual, bizarre shape, denoted by the term "ugly neurons", are proposed to be

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... considered as one of the criteria for the pathological manifestation of neuroplastic variability of projection neurons.