Management of Craniopharyngioma – Perspectives beyond Surgery and Endocrinology

Rachel K Crowley, Christopher J Thompson
2015 European Endocrinology  
The excess mortality in craniopharyngiomas is attributable to their size, site and the traditional surgical approach; aggressive resection predisposes to hypothalamic complications such as obesity, somnolence, thirst disorders and neurocognitive dysfunction. Recently, treatment has been modified to partial resection and radiotherapy. The role of the endocrinologist has expanded from identification and replacement of hormone deficits to include management of hypothalamic disease. Future
more » ... of craniopharyngioma with neo-adjuvant chemotherapy to minimise surgical resection may improve the outcomes for these patients.
doi:10.17925/ee.2015.11.02.96 pmid:29632577 pmcid:PMC5819074 fatcat:r663egxzjbfwpjjj6onpnybovy