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Stability of Gabexate Mesilate
1979
Japanese Journal of Hospital Pharmacy
Stability of gabexate mesilate (GM) in aqueous solution was studied. In buffer solutions at a constant pH between 1 and 7, hydrolysis of GM occurred in accordance with pseudo first-order kinetics. The stability of GM reached maximum at pH 3 and decreased with an increasing pH of buffer solution. Ionic strength did not influence the hydrolysis rate but concentration of buffer solution affected hydrolysis.
doi:10.5649/jjphcs1975.5.186
fatcat:reyrs55s7bgoxjbitolzi5sjgm