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Effect of dextromethorphan on antinociception and tolerance induced by swim-stress in the formalin test
2008
Archives of Iranian medicine
In the present study, the effect of dextromethorphan on antinociception and tolerance induced by water swim-stress in the formalin test was investigated. Swim-stress at 8 masculineC induces antinociception in both phases of the formalin test. Intraperitoneal administration of dextromethorphan (60 mg/kg) also induces antinociception in the second phase of the formalin test. The lower doses of dextromethorphan (1.25, 2.5, and 5 mg/kg) which did not induce antinociception alone, but did so in
pmid:18426320
fatcat:fgoddcshy5gptcjynqckeqe72u