Acute and delayed response of myostatin and insulin resistance to circuit resistance exercise
Recently, the role of myostatin (MSTN) in control of insulin resistance (IR( has been known. The purpose of this study was to determine of acute and delayed response of MSTN and IR to circuit resistance exercise. For this reason, 12 healthy men volunteered and participated in 2 sessions of the resistance exercise and control with one week apart from each others. After a session to be instructed on how to perform the resistance exercise and to be measured 1-RM, circuit resistance exercise
... nce exercise program was performed including 7 movements, and at each movement, 3 sets of 15 repetitions with a load 55% of 1 repetition maximum (1RM). In each session, blood samples were collected before, immediately after, 1 hour after and 24 hour after the exercise for measuring plasma myostatin, glucose and insulin concentration and IR was calculated. Using 2×4 repeated measures analysis of variance (ANOVA), exercise time had no significant effect on plasma myostatin concentration, so that plasma myostatin concentration increased immediately after the exercise and 1 and 24 hour after the exercise decreased gradually. Exercise time had a significant effect on plasma glucose and insulin concentration and IR, nevertheless, plasma glucose and insulin concentration and IR increased immediately after the exercise and 1 and 24 hour after the exercise decreased gradually. Interaction of session and time had no significant effect on plasma myostatin and glucose concentration, but a significant effect on plasma insulin concentration and IR. In conclusion, circuit resistance exercise can't have remarkable effects on acute and delayed response of MSTN and IR.