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Session 7: Molecular biology (III)
2002
Human Antibodies
Single-chain variable fragments (scFvs) are small tumor-recognition units that hold enormous potential in antibody-based therapeutics. Advantages of scfv over whole antibodies are now explored for radioimmunodetection and for insitu radiotherapy of cancer due to potentially better tumor penetration and blood clearance and reduced immunogenicity. Their clinical applications, however, require the large scale production and purification of biologically active recombinant scFvs. RM2 IgG1.k is a
doi:10.3233/hab-2002-111-207
fatcat:qn6vl2ovx5cx3nkdqjxuhtjcyq