A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Head-to-head comparison of the penetration efficiency of lipid-based nanoparticles in a 3D tumor spheroid model
[post]
2020
unpublished
<p>Most tumor-targeted drug delivery systems must overcome a large variety of physiological barriers before reaching the tumor site and diffuse through the tight network of tumor cells. Many studies focus on optimizing the first part, the accumulation of drug carriers at the tumor site, ignoring the penetration efficiency, i.e., a measure of the ability of a drug delivery system to overcome tumor surface adherence and uptake. We used 3D tumor spheroids in combination with light-sheet
doi:10.26434/chemrxiv.12136320
fatcat:ri5h2sjhabemrkucqkhcqc6bky