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A Case of Colchicine-Induced Neutropenia in Liver Cirrhosis Patient
Yeungnam University Journal of Medicine
Colchicine is an alkaloid that has been used for treating acute gouty arthritis, psoriasis, scleroderma and Behcet's syndrome. Colchicine decreased liver fibrosis in rats with carbon tetrachloride induced cirrhosis and in patients with many liver diseases. Therapeutic oral doses of colchicine may cause nausea, vomiting, abdominal pain and diarrhea. The adverse effect of colchicine associated with the dose is bone marrow suppression, and especially neutopenia. Neutropenia has often been reporteddoi:10.12701/yujm.2009.26.2.125 fatcat:zczjsvxdhfhgjohypiz2ku6xr4