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Canine Model of Cardiorenal Failure
Journal of Nephrology & Therapeutics
The heart and the kidneys act in tandem to regulate blood pressure, vascular tone, diueresis and to maintain intravascular volume homeostasis. Besides, the kidneys have a neuroendocrine function with interdependent physiological actions regulated by the renin-angiotensin-aldosterone system, sympathetic nervous system, and vasopressin and aterial natriuretic peptide. To investigate these complex pathophysiological mechanisms, a canine model for Congestive Heart Failure (CHF) compromised withdoi:10.4172/2161-0959.1000127 fatcat:hihcpcjhnvbvhgwwawu6vzmfmu