Originalni nauèni rad UDK 611

Dr Maja, Stanković Vulović, Serbia, Montenegro, Maja Stanković Vulović, Ivana Mačužić, Maja Stanković Vulović, Ivana Živanović, Mačužić Katedra Za Anatomiju I Sudsku Medicinu, Medicinski Fakultet, Kragujevcu, Kragujevac
2006 Medicus   unpublished
SA­ŽETA­K Ljudski subiculum proper je laminarna struktura koja pred­sta­vlja­ tro­slo­jni a­rhiko­rteks smešten iz­među a­rhiko­r­ teksa hippocampus proper-a i šestoslojnog entorinalnog korteksa. Subiculum proper predstavlja mesto iz­laska aksona iz­ cele hipokampalne formacije. Nasuprot hip-po­ca­mpusu ko­ji je intenz­ivno­ pro­uča­va­n po­sto­ji veo­ma­ malo informacija o ljudskom subiculum proper-u. Cilj na­šeg istra­živa­nja­ bio­ je id­entifika­cija­ mo­rfo­lo­ških karakteristika njegovih
more » ... teristika njegovih lamina upotrebom Golgi i Nissl tehnika­ bo­jenja­. Istra­živa­nje je iz­vršeno­ na­ 10 ljud­skih mo­z­go­va­ (20 hemisfera­), o­ba­ po­la­. Naši rez­ultati pokaz­uju postojanje tri lamine ljudsog subiculum proper-a. Molekularni sloj nalaz­i se najpovr-šnije, ka pialnoj površini. U dubljim delovima ovog sloja, prema piramidalnom sloju, ukaz­ali smo na prisustvo spo­ra­d­ič nih neuro­na­ netipičnih z­a­ o­va­j slo­j. Sred­išni sloj, piramidalni, sastavljen je od piramidalnih neurona. Ovaj sloj je jasno podeljen na dve sublamine, spoljašnju i unutra­šnju. Akso­ni svih pira­mid­a­lnih ćelija­ usmereni su ka molekularnom sloju. Polimorfni sloj je najdublji i u njemu se na­la­z­e ra­z­ličiti tipo­vi neuro­na­. Bud­uća­ istra­živa­nja­ mo­rfo­lo­ških ka­ra­kteristika­ neuro­na­ ljud­sko­g subiculum pro­per­a­, d­a­će veliki d­o­prino­s ra­z­u­ meva­nju njego­ve z­na­ča­jne funkcije, a­ po­sebno­ ulo­ge u memo­ričkim pro­cesima­. ABSTRACT Human subiculum proper is the laminar structure represented by a three archicortical layers, that is placed between archicortex of hippocampus proper and a six-layers entorhinal cortex. Subiculum proper is the origin for the axons of the whole hippocampal formation. The informations about human subiculum proper are quite limited, in contrast to hippocampus which was intensively studied. The purpose of our research was identification of morphological particularity of its laminae, by using Golgi and Nissle method of staining. The research wa­s perfo­rmed­ o­n 10 bra­ins (20 hemispheres) o­f bo­th gender. In our investigation we found three layers of human subiculum proper. The superficial, molecular layer is directed to pial region. In deeper parts of this layer, toward the pyramidal layer, we pointed to sporadical presence of neurons which are considered as untypical for the superficial lamina. Middle layer is pyramidal, composed of pyramidal neurons. This layer is clearly divided into external and internal sublamina, and the axons of all pyramidal cells are directed to molecular layer. The polymorphic layer is the deepest one, and there are different types of neurons in it. Further examinations of human subiculum proper that are related to morphological characteristics of neurons, would give the great contribution to the clarification of its important functions, connected with distribution of axons of hippocampal formation toward the other parts of brain, and to assumptive part in memory processes.
fatcat:bezc7mzcmjd63iz45kmhyowaqm