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Inhibition of neutrophil responses by cyclosporin A. An insight into molecular mechanisms
2001
Rheumatology
Objective. Cyclosporin A (CsA) is an effective agent in rheumatoid arthritis (RA), slowing joint damage progression. Its therapeutic effect on T lymphocytes has been studied extensively, but there is little information available about neutrophils, the cells responsible for a substantial proportion of in¯ammation. A study was performed to investigate the in vitro effects of CsA on neutrophil functions triggered by several agonists and determine whether the drug could counteract the binding of
doi:10.1093/rheumatology/40.7.794
pmid:11477284
fatcat:fnbxwlefhrg3hf7v4uierx5jh4