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LIQA: long-read isoform quantification and analysis
2021
Genome Biology
AbstractLong-read RNA sequencing (RNA-seq) technologies can sequence full-length transcripts, facilitating the exploration of isoform-specific gene expression over short-read RNA-seq. We present LIQA to quantify isoform expression and detect differential alternative splicing (DAS) events using long-read direct mRNA sequencing or cDNA sequencing data. LIQA incorporates base pair quality score and isoform-specific read length information in a survival model to assign different weights across
doi:10.1186/s13059-021-02399-8
pmid:34140043
pmcid:PMC8212471
fatcat:d4qtmrybpfezjouqmfyvvbyji4