Recovery Rate of Patients with Recurrent Ovarian Endometriomas Using Sclerotherapy with 95% Ethanol

Saeed Alborzi, Bahieh Namavar Jahromi, Morvarid Ahmadbeigi, Obstetrics and Gynecology Department, Medicine Faculty, Shiraz University Of Medical Sciences, Shiraz, Iran, Obstetrics and Gynecology Department, Medicine Faculty, Shiraz University Of Medical Sciences, Shiraz, Iran, Obstetrics and Gynecology Department, Medicine Faculty, Shiraz University Of Medical Sciences, Shiraz, Iran
2018 Journal of Obstetrics Gynecology and Cancer Research  
1] Management of ovarian endometrioma [2] Coagulation or excision of ovarian endometriomas? [3] Management of ovarian endometriomas [4] Management of endometriomas in women requiring IVF: to touch or not to touch [5] The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis [6] Impact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Müllerian hormone levels [7] Ten principles for safe surgical treatment
more » ... of ovarian endometriosis [8] The post-operative decline in serum antiMullerian hormone correlates with the bilaterality and severity of endometriosis [9] Effect of laparoscopic excision of endometriomas on ovarian reserve: serial changes in the serum antimüllerian hormone levels [10] Repeat transvaginal ultrasound-guided aspiration of ovarian endometrioma in infertile women with endometriosis [11] Rapid recurrence of endometrioma after transvaginal ultrasound-guided aspiration [12] Comparison of success rates of 'transvaginal aspiration and tetracycline sclerotherapy' versus 'only aspiration' in the management of nonneoplastic ovarian cysts [13] Ethanol sclerotherapy of ovarian endometrioma: a safe and effective minimal invasive procedure. Preliminary results [14] Ethanol sclerotherapy: a treatment option for ovarian endometriomas before ovarian stimulation [15] Aspiration and ethanol sclerotherapy to treat recurrent ovarian endometriomas prior to in vitro fertilization-a pilot study [16] Management of transvaginal ultrasound-guided absolute ethanol sclerotherapy for ovarian endometriotic cysts [17] Efficacy of ethanol sclerotherapy for ovarian endometriomas [18] Effectiveness of ultrasound-guided aspiration and sclerotherapy with 95% ethanol for treatment of recurrent ovarian endometriomas [19] Ultrasound-guided aspiration and ethanol sclerotherapy (EST) for treatment of cyst recurrence in patients after previous endometriosis surgery: analysis of influencing factors using a decision tree [20] Assessing the efficacy of aspiration and ethanol injection in recurrent endometrioma before IVF cycle: A randomized clinical trial [21] Surgery for endometriosis-associated infertility: a pragmatic approach Aims Ovarian endometrioma is a prevalent gynecologic disease in women of reproductive age that is accompanied with a number of symptoms and has a high recurrence rate after hormone therapy and surgery. The aim of this study was to evaluate the effectiveness of sclerotherapy with 95% ethanol in patients with recurrent ovarian endometriomas. Materials & Methods In this pre-post clinical trial, 14 patients with infertility and recurrent ovarian endometriomas were examined during a period from December 2012 to December 2013 in Ghadir Mother and Child Hospital affiliated with Shiraz University of Medical Sciences. These subjects had undergone a laparotomy to remove their cysts at least once. They were selected using convenience sampling method. The patients underwent sclerotherapy with 95% ethanol and referred 1, 3, 6, and 12 months after the procedure for their periodic examinations and levels of FSH, AMH, CA125, E2, AFC, mass size, and pelvic pain were measured. The data were analyzed using repeated measures analysis of variance (ANOVA) by SPSS 14 software. Findings While the level of FSH significantly decreased (p=0.01), the AMH level began to increase after the treatment (p=0.17); however, this increase was not significant. The AFC level increased with the aid of the treatment (p=0.002). The mass size and the patients' pain also significantly decreased (p<0.05). Four cases of pregnancy happened. In 2 of the patients, the cysts recurred and grew again. Conclusion Sclerotherapy with 95% ethanol can be used as an appropriate alternative therapy in patients with recurrent endometriomas.
doi:10.30699/jogcr.3.3.105 fatcat:4ektwpzblndh7g2tmfi7kh6qhy