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Analysis of the role of Chest X-Ray in a large cohort of 1117 patients with SARS-CoV-2 infection: an Italian multicenter study [post]

Valentina Vespro, Maria Carmela Andrisani, Stefano Fusco, Letizia Di Meglio, Guido Plensich, Alice Scarabelli, Elvira Stellato, Annamaria Ierardi, Luigia Scudeller, Andrea Coppola, Andrea Gori, Antonio Pesenti (+18 others)
2020 unpublished

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Objective. To describe the radiographic key patterns on CXR in patients with SARS-CoV-2 infection, assessing the prevalence of radiographic signs of interstitial pneumonia. To evaluate pattern variation between a baseline and a follow-up CXR.Materials and methods. 1117 patients tested positive for SARS-CoV-2 infection were retrospectively enrolled from four centers in Lombardy region. All patients underwent a CXR at presentation. Follow-up CXR was performed when clinically indicated.Two
more » ... ists in each center reviewed CXR images and classified them as suggestive or not for interstitial pneumonia, recording the presence of ground-glass opacity (GGO), reticular pattern or consolidation and their distribution.Pearson's chi-square test for categorical variables and McNemar test (chi-square for paired data) were performed.Results. Patients mean age 63.3 years, 767 were males (65.5%). The main result is the large proportion of positive CXR in COVID-19 patients.Baseline CXR was positive in 940 patients (80.3%), with significant differences in age and sex distribution between patients with positive and negative CXR. 382 patients underwent a follow-up CXR. The most frequent pattern on baseline CXR was the GGO (66.1%), on follow-up was consolidation (53.4%). The most common distributions were peripheral and middle-lower lung zone.Conclusions. We described key-patterns and their distribution on CXR in a large cohort of COVID-19 patients: GGO was the most frequent finding on baseline CXR, while we found an increase in the proportion of lung consolidation on follow-up CXR. CXR proved to be a reliable tool in our cohort obtaining positive results in 80.3% of the baseline cases.
doi:10.21203/rs.3.rs-28697/v1 fatcat:wimofhducrcfphlxtrftyuqn7q
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Valentina Vespro, Maria Carmela Andrisani, Stefano Fusco, Letizia Di Meglio, Guido Plensich, Alice Scarabelli, Elvira Stellato, Annamaria Ierardi, Luigia Scudeller, Andrea Coppola, Andrea Gori, Antonio Pesenti, Giacomo Grasselli, Stefano Aliberti, Francesco Blasi, Chiara Villa, Sonia Ippolito, Barbara Pirrò, Guglielmo Damiani, Massimo Galli, Giuliano Rizzardini, Emanuele Catena, Matteo Agostino Orlandi, Sandro Magnani, Giuseppe Cipolla, Andrea Antonio Ianiello, Mario Petrillo, Genti Xhepa, Alberto Cazzulani, Gianpaolo Carrafiello. "Analysis of the role of Chest X-Ray in a large cohort of 1117 patients with SARS-CoV-2 infection: an Italian multicenter study." (2020)