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Natural products play a significant role in drug discovery and development. Many topological pharmacophore patterns are common between natural products and commercial drugs. A better understanding of the specific physicochemical and structural features of natural products is important for corresponding drug development. Several encyclopedias of natural compounds have been composed, but the information remains scattered or not freely available. The first version of the Supernatural databasedoi:10.1093/nar/gku886 pmid:25300487 pmcid:PMC4384003 fatcat:y25eyjcn6zfplisglawwhy3tni