Effect of Intrathecal Dexmedetomidine Bupivacaine Combination on Duration of Subarachnoid Block and Post Operative Analgesia

Dr. Rachana joshi, Dr. Jignesh mori, Dr. Kamla H Mehta
2012 International Journal of Scientific Research  
Objective: This study aims to compare efficacy of intrathecal bupivacaine with intrathecal bupivacaine dexmedetomidine combination on duration of subarachnoid block and post operative analgesia. Methods: This study included 50 patients of ASA grade І/ІІ posted for lower abdominal surgery. Patients were divided in to 2 groups: group B received (n=25) received 0.5% heavy bupivacaine 3ml( 15mg) with 0.9% normal saline 0.2ml intrathecally. group BD received (n=25) received 0.5% heavy bupivacaine
more » ... eavy bupivacaine 3ml( 15mg) with dexmedetomidine 0.05ml (5µg) and 0.9% normal saline 0.15ml intrathecally. Onset and duration of sensory and motor blockade, duration of analgesia and side effects were recorded. Results: Dexmedetomidine significantly prolonged the duration of analgesia and duration of sensory and motor block as compared to intrathecal bupivacaine alone. No significant side effects were reported between two groups. Conclusion: In conclusion, 5μg dexmedetomidine is an attractive alternative as adjuvant to spinal bupivacaine in surgical procedures especially in those that need quite long time with minimal side effects and excellent quality of spinal analgesia.
doi:10.15373/22778179/feb2013/97 fatcat:fpiismmkwzaodgx22abehico7u