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Repair of ultraviolet light-damaged deoxyribonucleic acid in sbc-A strains of Escherichia coli K-12

D M Shlaes, S D Barbour
1979 Journal of Bacteriology  

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An Escherichia coli strain carrying both rec+ and sbcA has been constructed. Repair of ultraviolet light-induced deoxyribonucleic acid damage was examined by measuring survival and thymine-dimer excision in the rec+ sbcA strain as well as rec+ sbcA+ and recB recC sbcA strains. The sbcA mutation restores normal survival in both recB recC uvrB and recB recC uvrr strains. Excision of thyminecontaining dimers does not occur in uvrB mutants, regardless of the rec or sbcA genotype. Survival, after
more » ... raviolet-light damage, of a rec+ sbcA strain is quantitatively similar to rec+ sbcA+ and recB recC sbcA strains. 30. Yajko, D. M., M. C. Valentine, and B. Weiss. 1974. Mutants of E. coli with altered DNAses. II. Isolation and characterization of mutants for exonuclease I. J.
doi:10.1128/jb.138.1.105-108.1979 fatcat:xe4klknrzncqjagg3y54fqz7qi
Citation

D M Shlaes, S D Barbour. "Repair of ultraviolet light-damaged deoxyribonucleic acid in sbc-A strains of Escherichia coli K-12." Journal of Bacteriology 138.1 (1979) 105-108