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Vaccines against Toxoplasma gondii: challenges and opportunities
Memórias do Instituto Oswaldo Cruz
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects. Rodent models have been used in research on vaccines against T. gondii over the past decades. However, regardless of the vaccine construct, the vaccines have not been able to induce protective immunity when the organism is challenged with T. gondii, either directly ordoi:10.1590/s0074-02762009000200019 pmid:19430651 fatcat:b42fmt66pjfiznop3a6s4cvq5a