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Enrichment of neural-related genes in human mesenchymal stem cells from neuroblastoma patients
2012
International Journal of Molecular Medicine
Neuroblastoma (NB) is one of the most common pediatric solid tumors and, like most human cancers, is characterized by a broad variety of genomic alterations. Although mesenchymal stem cells (MSCs) are known to interact with cancer cells, the relationship between MSCs and metastatic NB cancer cells in bone marrow (BM) is unknown. To obtain genetic evidence about this interaction, we isolated ΒΜ-derived MSCs from children with NB and compared their global expression patterns with MSCs obtained
doi:10.3892/ijmm.2012.1008
pmid:22641458
fatcat:dzpy7gvdkzcmrpv6ole6wgeejq