A man, 55 years old, was found by the police, confused, in the street, in November, 1900. He was taken to the Philadelphia General Hospital, where he had an attack of excitement and violence lasting a couple of days. Since then he has had no recollection of his past life for some years previous, and cannot remember anything that happens now even for a few minutes. The events of his childhood, youth and early man¬ hood and the things that he learned at school he remembers fairly well. He knows

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... at he has been married, but does not know whether his wife is living or dead, and says he has forgotten entirely what she looks like. When he is spoken to about his wife he becomes emotional, but in a few minutes forgets all about it. He knows who he is and has never had any alteration in personality. He is neat and clean in his habits, quiet in manner and shows no moral defect. He knows that he has lost his memory and knows that it is on account of disease. His intellectual judgment is much better than is usually found in senile or presenile dementia. His loss of memory is so great that if he reads (and he reads well) a paragraph in a newspaper he forgets the first sentence before he has read the last. Though he has been told many times that he is in the Philadelphia General Hospital he can never remember it. When in the ward he can reason out that he is in a hospital on account of the number of beds and the presence of people manifestly sick. When he is in the hospital office, however, he reasons out that he must be in some business house on account of the number of desks and clerks. He cannot tell five minutes after a meal whether he has had a meal or not, but reasons that since he is not hungry he must have been fed. He does not know the year, the month or the season of the year. He remembers the year of his birth, but does not know how old he is because, as he says, "I do not know what year this is." In the last few months a few things have made some impression on him, for he now vaguely realizes all the time that he is being treated in a hospital for his sickness. Dr. B. Sachs said the condition was an extremely interesting one, and the only cases that he has seen that have been equally puzzling have been cases entirely different from the one presented. Two years ago he saw a man who developed an amnesia which was as complete as that of the patient presented, and even more complete. He lost memory of his own personality. He developed this amnesia as an early symptom of general paresis. A few weeks later he developed general paresis with very characteristic symptoms and passed more than a year as an inmate of an