Anaplastic Large Cell Lymphoma Associated with Saline Breast Implant

Grace Ng, Rupa K. Patel, LaNette Smith, Guido Sclabas
2016 Archives of Breast Cancer  
Breast implant associated anaplastic large T- cell lymphoma is a rare type of non-Hodgkin lymphoma, with a reported incidence of 0.3% per 100,000 women with breast prosthesis per year. It presents most commonly as a peri-implant seroma, but may also present as a capsular mass, tumor erosion through skin, in a regional lymph node, or found incidentally during revision surgery. Case presentation: We report a 68-year-old female patient who presented with a four month history of marked pain and
more » ... ling of the right breast, who upon implant removal and right sided capsulectomy, revealed pathology consistent with ALK negative, CD 30 positive anaplastic large T- cell lymphoma. Conclusion: Breast implant associated anaplastic large cell lymphoma, although a rare clinical occurrence is of clinical significance. Prognosis is favorable in the majority of reported cases. Definitive treatment guidelines have yet to be determined after review of long-term follow-up data.
doi:10.19187/abc.201634135-138 doaj:49c2023ae20c479082e87ac27fada69c fatcat:5rn63qpipfci3mlhykongbzrai