Cutaneous squamous cell carcinoma(cSCC)normally spreads to locations close to the primary lesion. We describe an extremely rare case of brain metastasis from cSCC in a 47-year-old female who had undergone removal of lower leg cSCC (T2N0M0) 2 years previously. She was admitted to our hospital with dizziness. Contrast-enhanced computed tomography imaging showed a cerebellar lesion with contrast effect. We performed surgical removal and histological examination revealed that the lesion was

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... is from lower leg cSCC. She was given radiotherapy for the residual tumor(39 Gy) . After the operation and radiotherapy, magnetic resonance imaging showed significant reduction in the size of the residual tumor and the posttreatment course was uneventful. No standard treatment strategy for brain metastasis from cSCC has been established. Therefore, further investigations are needed to establish an effective treatment for these tumors.