A two year register of ACS in 658 patients was drawn in the conditions of the Fergana valley in Uzbekistan. It was proved that the register helps objectively view the problems of the approach to treatment and «saving» prevention of the patients with acute coronary syndrome (ACS) and find solutions for them. In the conditions of the research region, they are acceptable, cost-effective and efficient in optimization of methods of early detection and treatment of ACS. Аbstract: When hepatitis

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... ogenesis marked imbalance in the system of lipid peroxidation and antioxidant enzyme system. Pharmacotherapy cytostatic leads to even greater intensification of lipid peroxidation. Thus activity of antioxidant defense enzymes even more oppressed. Roncoleukin results to some rebalancing of the system of lipid peroxidation and antioxidant enzyme systems. Which has a temporary nature. The combined use of doxorubicin and ronkolejkin some what reduces the marked of doxorubicin hyperlipidperoxidation and increases the activity of antioxidant enzymes. Keywords: hepatocarcinogenez, system of lipid peroxidation and antioxidant enzyme systems.