Urinary Sulfated Bile Acids in Alcoholics

Gaoyuan Meng, Fumiko Mashige, Katsuya Maruyama, Masayuki Nakano, Akiyuki Ohkubo
1994 Japanese Journal of Clinical Chemistry  
The levels of urinary total sulfated bile acids (U-TSBA) in 12 social alcohol drinkers and 20 heavy drinkers with liver diseases were investigated. In comparison with the reference value, no significant elevation of U-TSBA was found in either group regardless of the severity of alcoholic liver injury. Two of the three heavy drinkers with abnormal values of U-TSBA were positive for hepatitis C virus antibody and showed corresponding histological compatible with viral hepatitis. The results show
more » ... hat alcoholic liver injury per se may have minimal effects, if any, on urinary sulfated bile acid excretion, while other hepatobiliary diseases including viral hepatitis result in significant increases.
doi:10.14921/jscc1971b.23.4_323 fatcat:j3jeelrlazfpjcxsavxbuykmam