Turning the clock back on ancient genome duplication

Cathal Seoighe
2003 Current Opinion in Genetics and Development  
Complete genome sequence data led rapidly to the conclusion that ancient genome duplications had shaped the genomes of the model organisms Saccharomyces cerevisiae and Arabidopsis thaliana. Recent contributions have gone on to refine date estimates for these duplications and, in the case of Arabidopsis, to infer additional, more ancient, rounds of duplication by reconstructing gene order before the most recent duplication event. It is becoming widely accepted that an ancient duplication
more » ... before the radiation of the ray-finned fish. However, despite methodological advances and the availability of complete genome sequence data the debate over whether very ancient genome duplications have occurred early in the vertebrate lineage has not yet been fully resolved.
doi:10.1016/j.gde.2003.10.005 pmid:14638327 fatcat:byfexllewza2derh54ok3rwudq