Follicular helper T lymphocytes in health and disease

Cecilia Parodi
2014 World Journal of Hematology  
Core tip: Follicular helper T lymphocytes (TFH) are essential to establish a correct and protective humoral immune response. Correct regulation of their development and differentiation is necessary to achieve a normal antibody response. They can be characterized by their phenotype and function. It has been proposed that their role is important in the generation of immunodeficiency or autoimmunity, as well as in the control of chronic viral or protozoan infections. This review comments recent
more » ... comments recent advances in human TFH research that may be useful in order to design adequate therapeutic or vaccination strategies.
doi:10.5315/wjh.v3.i4.118 fatcat:isyokr3qgbcqboazbrdtu5rism