BACKGROUND: Succinylcholine is widely used to facilitate intubation but it is contraindicated and hazardous in some medical conditions and Rocuronium is safer alternative. Aim: To study the intubating conditions obtained after different doses of Rocuronium and to compare with succinylcholine. SETTING AND DESIGN: Randomized and prospective study. METHODS: 100 adult patients posted for major surgeries under general anaesthesia divided into four groups of 25 each depending on dose and muscle

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... nt given. Intubating conditions were assessed using standard scoring system, results were tabulated and analysed. STATISTICAL ANALYSIS: Results were analysed using chi-square test and unpaired t test. RESULTS: Intubating conditions after Rocuronium 0.6 mg/kg body weight at 90 seconds and Rocuronium 0.9 mg/kg body weight at 60 seconds are clinically acceptable in 100% of the patients and are equivalent to succinylcholine 1.5 mg/kg BW. CONCLUSION: Rocuronium is alternative and safer choice of succinylcholine in the conditions where succinylcholine is contraindicated and hazardous.