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Number of Negative Points: A novel method for predicting radiosensitivity in head and neck tumor cell lines
The present study was aimed at establishing a method that combines multiple factors of protein and genetic changes that enables prediction of radiosensitivity in the head and neck squamous cell carcinoma (HNSCC) cell lines. In nine HNSCC cell lines, the quantity of protein expression and the type of genetic alterations were translated into a point system, called the Number of Negative Points. The expression of 14 proteins involved in growth control and/or apoptosis was quantified using adoi:10.3892/or_00000028 fatcat:em6i4gwyyba7ff47zvlasmxmem