RESIDUE DEPLETION OF SULPHADIAZINE AND TRIMETHOPRIM IN PIGS AND BROILERS AFTER ORAL ADMINISTRATION

P Roncada, L Tomasi, F Sori, A Zaghini, A Zaccaroni, D Ferrara
2012 Online Journal of Animal and Feed Research   unpublished
The residual behaviour of a sulphadiazine (SDZ) and trimethoprim (TMP) combination was studied in fourteen pigs and twenty-eight broilers. The drug combination was added in the amount of 700 mg kg-1 (SDZ) and 140 mg kg-1 (TMP) to pig and 300 mg kg-1 (SDZ) and 60 mg kg-1 (TMP) to broiler feed, respectively. The medicated feeds were supplied for 5 consecutive days. The tissue SDZ/TMP concentrations were measured by a HPLC method. To ensure safe residue levels in all target tissues, withdrawal
more » ... of 8.6 days and 6.0 days should be applied to pigs and broilers, respectively, treated with SDZ and TMP in feed.
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