Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms

Stephen M. Stahl
2013 CNS Spectrums  
ISSUE:The low incidence of extrapyramidal side effects associated with the atypical antipsychotic iloperidone may be linked to its unique binding profile of high affinity antagonism of both α1 adrenergic receptors and serotonin 2A receptors.
doi:10.1017/s1092852913000850 pmid:24300463 fatcat:kkpq5nl445hzpda72m3fp7hah4