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African histoplasmosis is a mycotic infection mostly confined to Madagascar, Western and Central Africa with a few rare cases reported outside these endemic areas. Despite being in the endemic zone, few cases have been reported from Ghana. A 36 year old woman developed inexplicable left knee pain and four months later noticed nodular eruptions at the posterior aspect of her neck which subsequently spread to involve other body areas. She had associated generalized lymphadenopathy but nodoi:10.5281/zenodo.4316510 fatcat:tezrwylyona27ka4j4phgbsnky