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In vitro models for assessing the potential cardiovascular disease risk associated with cigarette smoking
Toxicology in Vitro
Atherosclerotic cardiovascular disease is a prevalent human disorder and a significant cause of human morbidity and mortality. A number of risk factors may predispose an individual to developing atherosclerosis, and of these factors, cigarette smoking is strongly associated with the development of cardiovascular disease. Current thinking suggests that exposure to toxicants found in cigarette smoke may be responsible for this elevated disease likelihood, and this gives rise to the idea thatdoi:10.1016/j.tiv.2012.08.018 pmid:22951947 fatcat:76hpvgh5pfatnbveldjtbqsh7a