An efficient synthesis of E-2-amino-4-aryl-8-(arylmethylene)-5,6, 7,8- tetrahydrobenzo[d]pyrimid!nes and their lower analogues

Rammohan Pal, Tapas K. Mandai, Swati Samanta, Asok K. Mallik
2010 Zenodo  
Department of Chemistry, Jadavpur University, Kolkata-700 032, India E-mail : Manuscript received 4 November 2009, accepted 27 November 2009 Base-catalyscd cyclocondensation of α,α'-bis(arylmethylene)cyclohexanones with guanidine hydrochloride has been found to generate E-2-amino-4-aryl-8-(arylmethylene)-5,6,7,8-tetrahydrobenzo[d]pyrimidines in high yield, the structures or which have been established from their analytical and spectral data. The corresponding lower
more » ... es, α,α'- bis(arylmethylcne)cyclopcntanones also were found to produce similar products viz. E-2-amino-4-aryl-7-(arylmethylene)- cyclopenteno[1,2-d]pyrlmidines in comparable yield under the same reaction condition.
doi:10.5281/zenodo.5790642 fatcat:pg2tfyswkzc7plab7ubmcvuvzy