Access to a stabilized i-motif DNA structure through four successive ligation reactions on a cyclopeptide scaffold

Alexandre Devaux, Laureen Bonnat, Thomas Lavergne, Eric Defrancq
2020 Organic and biomolecular chemistry  
I-motifs are largely underexplored tetraplex nucleic acid structures which have been suggested to play essential biological functions and might constitute future therapeutic targets. I-motifs generally require acidic conditions to fold...
doi:10.1039/d0ob01311k pmid:32756719 fatcat:hd2x5n47knfolgldeu5jnheqei