Meningosarcoma represent a rare disease with an uncertain prognosis. Moreover, localization of tumours in the infratemporal fossa is rare. Lack of associated symptomatology of infratemporal fossa's lesions could result in a diagnosis and treatment delay. Also, surgical management of infratemporal fossa neoplasm remain challenging. Case presentation: The authors present the case of a meningosarcoma extended to the infratemporal fossa, which presented in an advanced stage and required other

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... ent further than surgery. Conclusion: A comprehensive histological evaluation and a multidisciplinary team help making the diagnosis and managing all eventualities. Sometimes surgery is not enough, and more therapeutic strategies are necessary.