BackgroundRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by intra-articular manifestations affecting small and large joints. Hip involvement is not common but it can predict a severe disease course [1].ObjectivesOur study aimed to investigate the prevalence of coxitis in RA patients and to compare patients with RA coxitis (+) and RA coxitis (-) according to their clinical, biological outcomes and their therapeutic findings.MethodsThis was a retrospective and

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... e study, which include patients diagnosed with RA according to the ACR/EULAR 2010. Sociodemographic, clinical, biological, and therapeutic data were collected. The diagnosis of coxitis was made on plain x-rays or MRI.ResultsAmong 255 RA, there were 30 RA coxitis (+) (11.8%). Coxitis was unilateral in 28 patients and bilateral in 2 patients. The mean delay onset of coxitis was about 11.6 ± 8.4 years (1-27). The mean age was 57.5 ± 12.2 years for RA coxitis (+) and 59.1 ± 10.5 years for RA coxitis (-) (p=0.5). The gender distribution was (70% female and 30% male) for RA coxitis (+) and (85% female and 15% male) for RA coxitis (–) (p= 0.04). The mean Body Mass Index was 24.8 ± 4.8kg/m2 in RA coxitis (+) and 28 ± 5.8 kg/m2 in RA coxitis (-) (p= 0.03). Comorbidities were present in 46% of RA coxitis (+) and 48% of RA coxitis (–) (p=0.8). Extra articular manifestations were noted in 76% RA coxitis (+) and 66% RA coxitis (–) (p=0.8). RA was seropositive in 76% RA coxitis (+) and in 82% RA coxitis (–) (p=0.4). RA was immunopositive in 51% RA coxitis (+) and 69% RA coxitis (–) (p=0.04). The mean DAS28 (CRP) was respectively 4.6± 1.1 in RA coxitis (+) vs 4.8 ± 1.1 RA coxitis (-) (p=0.7). Atlanto-axial dislocation was noted in 60% RA coxitis (+) and 22% RA coxitis (–) (p<10-3).The use of corticosteroid was noted in 92% RA coxitis (+) and in 90% RA coxitis (–) (p=0.7). Biologic drugs were prescribed in 43% RA coxitis (+) and in 25% RA coxitis (–) (p=0.04).ConclusionOur study showed that coxitis in RA patients is associated with a higher risk of Atlanto-axial dislocation and a more frequent use of biologic drugs reflecting a more severe and mutilating disease. We highlight the importance of an early diagnosis and treatment to prevent complications.References[1]Bajraktari IH, Krasniqi B, Rexhepi S, Bexheti S, Bahtiri E, Bajraktari H, Luri B. Prevalence of Coxitis and its Correlation with Inflammatory Activity in Rheumatoid Arthritis. Open Access Maced J Med Sci. 2018;6(2):336-339.Disclosure of InterestsNone declared