A Method to Characterize Calcium Activity in Stimulated Cultures of Cardiac Myocytes

Raul Benitez, Alex Vallmitjana, Leif Hove-Madsen
2013 Biophysical Journal  
Ca 2þ loss from these intracellular stores, not from the extracellular space, we developed a flexible in vitro 3D skin equivalent model that allows intraorganelle monitoring of calcium levels by genetically encoded sensors. These new findings suggest that long-held hypotheses addressing Ca 2þ control of differentiation and barrier formation require revision.
doi:10.1016/j.bpj.2012.11.3365 fatcat:gnuroghpobb3zbynpig5kexaw4