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Therapeutic hypothermia is a strategy to lower core body temperature to achieve neuroprotection, and is increasingly used in the intensive care unit. This therapy has strong evidences to protect the brain in patients with hypoxic-ischemic insults from cardiac arrest and perinatal asphyxia. Therapeutic hypothermia also has beneficial effects on the reduction of brain edema and intracranial pressure. Other types of brain injuries have off-label indications and are likely to gain strongerdoi:10.18700/jnc.2015.7.1.6 fatcat:ajvbelauknasvfq7hixqyabkii