Gastro-oesophageal reflux: an overview of the pharmacotherapeutic treatment options

L Malan, Q Labuschagne, N Schellack, G Schellack, J C Meyer
2017 South African Family Practice  
Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g. acid production, thereby providing relief. Currently available agents include simple antacids and acid suppression therapy, including histamine 2-receptor antagonists, proton pump inhibitors, mucosal or cytoprotective agents and pro-motility agents. Deciding on appropriate therapy
more » ... propriate therapy will depend on the diagnosis, side-effects and cost-effectiveness of the treatment.
doi:10.4102/safp.v59i3.4687 fatcat:3wrq2kzwwrgxxicu6zoyxqsv7m