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Polygenicity And Epistasis Underlie Fitness-Proximal Traits In TheCaenorhabditis elegansMultiparental Experimental Evolution (CeMEE) Panel
[article]
2017
bioRxiv
pre-print
Understanding the genetic basis of complex traits remains a major challenge in biology. Polygenicity, phenotypic plasticity and epistasis contribute to phenotypic variance in ways that are rarely clear. This uncertainty is problematic for estimating heritability, for predicting individual phenotypes from genomic data, and for parameterizing models of phenotypic evolution. Here we report a recombinant inbred line (RIL) quantitative trait locus (QTL) mapping panel for the hermaphroditic
doi:10.1101/120865
fatcat:5bxi2jutxbh27fwiodxuwy6npy